A man is shot and quickly buried in the high desert of west Texas. The body is found and reburied in Van Horn's town cemetery. Pete Perkins, a local ranch foreman, kidnaps a Border Patrolman and forces him to disinter the body. With his captive in tow and the body tied to a mule, Pete undertakes a dangerous and quixotic journey into Mexico.

The Burning Plain follows the story of several different people separated by time and space -- Sylvia, a woman in Oregon who must undertake an emotional odyssey to rid herself of her past; Mariana and Santiago, two teenagers trying to piece together the shattered lives of their parents in a New Mexico border town; Maria, a little girl who goes on a border-crossing voyage to help her parents find redemption, forgiveness, and love; and Gina and Nick, a couple who must deal with an intense and clandestine affair... because they are both married.